Representative SELDI-TOF MS spectra from plasma from patients with SCD with and without PAH. The vertical axes represent intensity of peaks in arbitrary units, and the horizontal axes represent mass to charge ratio (m/z). These 4 spectra were obtained from plasma eluted from ion anion exchange resin, bound to IMAC30-Cu⁺⁺ matrix, and ionized for SELDI-TOF MS. Two specimens are from SCD patients without PAH (A,B) and 2 are from SCD patients with PAH (C,D). A peak at m/z 28.1 kDa was observed at lower average intensity in SCD patients with PAH ().