Overall survival in patients with DLBCL. (A) Overall survival of 31 patients with de novo DLBCL who received DA-EPOCH-B. With a median potential follow-up of 49 months, the median survival was 8 months. B. (B) Overall survival of 27 patients with ABC or GCB DLBCL who received DA-EPOCH-B showed a median survival of 10.8 and 3.4 months, respectively (P = .0026). (C) Overall survival of 54 patients with de novo DLBCL whose disease progressed after R-CHOP. With median potential follow-up of 22.5 months for survivors, the median survival was 5.6 months. (D) Overall survival of 50 patients with ABC or GCB DLBCL whose disease progressed after R-CHOP showed a median survival of 5.8 and 9.5 months, respectively (P = .93).