Changes in T-cell counts after rhIL-7 administration. (A) CD4⁺ and CD8⁺ T-cell counts decreased significantly on days 1 and 2 and increased significantly on day 14 after the rhIL-7 dose. ● represents placebo participants () and ▲ represents rhIL-7 participants (). (B) CD4⁺ and CD8⁺ T-cell changes from baseline according to rhIL-7 dose group. ● represents placebo participants () and rhIL-7 participants are represented by ▲ (3 μg/kg), ■ (10 μg/kg), ♦ (30 μg/kg), and X (60 μg/kg). (C) Central memory CD4⁺ and CD8⁺ T cells decreased significantly on day 1 and increased significantly on day 14 and day 28 (CD8⁺ T cells) after a single rhIL-7 administration. ● represents placebo participants () and ▲ represents rhIL-7 participants ().