Figure 3
![Figure 3. Differential expression of MYC targets in miRNA-driven subsets of DLBCL. Box plot display of the real-time RT-PCR analyses of 3 independent MYC target genes, CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase), PGK1 (phosphoglycerate kinase 1), and TFAM (transcription factor A, mitochondrial) in 24 primary DLBCL samples (16 assigned to MG-A and 8 to MG-C). As hypothesized, MYC activity, defined by the expression of these target genes, was significantly higher in MG-A tumors (P < .01, Mann-Whitney test [CAD and PGK1] and P < .05 [TFAM]).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/113/26/10.1182_blood-2009-01-202028/4/zh89990935560003.jpeg?Expires=1735829680&Signature=g5YP7O6vkuUd3Ul-jDCYBPHwrWooByuJK9tD5Ax0yd9tmU7Gj83z~4g-RRJjRW0q4bZ1a2YZR1ieTkTPZy~sihqjHplF928ZVMB9Ze4LNS6-pOc1uc8UopyVs995J5hKRF3D1xouu4z0UAK5Pa4nO0-9zbnBPdO7DyNBPdphc6fmi9z4S9bsFsoxNbcagOKPXpgtDcbTbGfTpSpO0CQZ4kpbg7uQyhnMiivcOKySy9sVvfALdwDsvZECR4vkzSRabE1W5tZiBm8WvCxz9GSdu5vvvB7ROw1r~a-Fcrz70LR7Yix27u-VJ0D6BInbjbhZ0dKVyud20~aoWQswPwcRGQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Differential expression of MYC targets in miRNA-driven subsets of DLBCL. Box plot display of the real-time RT-PCR analyses of 3 independent MYC target genes, CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase), PGK1 (phosphoglycerate kinase 1), and TFAM (transcription factor A, mitochondrial) in 24 primary DLBCL samples (16 assigned to MG-A and 8 to MG-C). As hypothesized, MYC activity, defined by the expression of these target genes, was significantly higher in MG-A tumors (P < .01, Mann-Whitney test [CAD and PGK1] and P < .05 [TFAM]).
