aGVHD delays the naive CD4 T-lymphocyte reconstitution. T-cell subset reconstitution was measured by flow cytometry before and 3, 6, 12, and 24 months after transplantation on patients with (, plain gray lines, n = 68) or without aGVHD (●, dotted black lines, n = 25). Mean ± SE CD4+ (A), CD8+ (B), naive CD4+CD45RA+CD62L+ (C), or naive CD8+CD45RA+CD62L+ (D) T cells/mm3 were represented. *P < .05.