Activin A up-regulates CXCL14 and CXCL12 in DCs. (A) Low-density microarray of DC mRNA extracted after 1 and 8 hours of activin A (100 ng/mL) stimulation. The data are expressed as fold of induction versus control DC. Only regulated chemokines are shown. (B,C) Kinetics of CXCL14 and CXCL12 release by 100 ng/mL activin-A–stimulated DC. SB431542, an ALK4 inhibitor, was used at the concentration of 5 μM. Data are the mean plus or minus SD of 4 independent experiments. *P < .05, **P < .005 by paired Student t test versus control groups.