Phagocytosis of platelet-derived microvesicles by splenic macrophages in mice. Splenic macrophages were isolated from lactadherin-deficient mice and their wild-type littermate controls and incubated with BODIPY-labeled mouse platelet-derived microvesicles in the absence or presence of exogenous lactadherin. Phagocytosis of microvesicles was quantified as described before. The results are the means and SDs of triplicate measurements.