The levels of histamine, LTs, and PGD2 release by MPD HCMCs. HCMCs from 11 MPD patients and 6 Gmob volunteers were sensitized with IgE overnight and then were challenged with or without anti-IgE for 30 minutes at either 37°C or 42°C (105/mL). The levels of histamine (A,D), PGD2 (B,E), and LTs (C,F) in the supernatants were measured by ELISA. Each triangle represents the level of histamine in the supernatants of HCMCs sensitized with IgE (A-C) or HCMCs stimulated with IgE plus anti-IgE (D-F) at the temperature indicated. Each bar represents the mean of each sample group.