Correlation of pruritus with the abnormal functions of MPD MCs, plasma levels of IL-31, and JAK2V617F allele burden. The correlation between patients with or without a complication of pruritus with (A) the number of MCs produced by 10⁶ PB CD34⁺ cells, (B) the number of MC colonies formed by 10³ PB CD34⁺ cells, (C) percentage of apoptotic HCMCs on overnight starvation, (D) the levels of PGD₂ released by IgE + anti-IgE stimulated MCs, (E) the plasma levels of IL-31, and (F) granulocytes JAK2V617F allele burden were determined using a 2-tailed Student t test. Each bar represents the mean of each sample group.