Sequence conservation between Lmo2 loci from eutherian mammals and opossum identifies 15 distal candidate regulatory elements. MVista representation of sequence conservation across 250 kb of the mouse Lmo2 locus. The conservation panels correspond to, from top to bottom, mouse/human, mouse/dog, mouse/cow, and mouse/opossum alignments. The conservation plots show regions with at least 50% of conservation (y-axis) across the 250-kb tiling path spanning the mouse Lmo2 locus, where the translation initiation (ATG) is marked as position 0 (x-axis). Shown at the top of the figure are exons with arrows pointing in the direction of transcription. The gray lines indicate promoters, and the black lines highlight the 15 noncoding conserved regions between opossum and eutherian sequences. The positions of the conserved regions are named relative to the ATG of Lmo2 and depicted in the box at the bottom of the figure (black), together with the distal (dp) and proximal (pP) Lmo2 promoters (gray).