WT1 aberrations in patient no. 1885 detected by array-CGH and sequencing. (A) The left part of the figure shows a chromosome 11 ideogram and corresponding oligonucleotide array-CGH plot of the ratio of patient no. 1885 DNA and control DNA (blue tracing) versus the dye-swap experiment (red tracing) from an array-CGH experiment (105-K oligonucleotide array-CGH platform; Agilent Technologies, Palo Alto, CA). A cryptic 11p13 deletion of approximately 2.5 Mb is found, which area includes the WT1 gene. The right part of the figure zooms in on the deleted area and presents the genes located in this area. (B) Sequence analysis of patient no. 1885 showing a c.901C→T non-sense mutation on the remaining WT1 allele.