Tumor phenotype and prevalence in mice reconstituted with v-abl transgenic fetal liver as a function of Blimp1 gene dose. (A) Kaplan-Meier plot of PCT incidence by Blimp1 genotype (●, Blimp1^+/+; ○, Blimp1^gfp/+, ▴, Blimp1^gfp/gfp). See “Methods” for statistical analyses. (B) Native gel electrophoresis to reveal paraprotein (*) in the serum of PCT-bearing mice. Vertical lines (white) have been inserted to indicate gel lanes repositioned to juxtapose relevant samples; sera were run in batches on different days, but the NMS control included on each gel is shown in the figure. (C) Flow cytometric analyses of cells from tumors, BM, and spleens of mice reconstituted with Blimp1^+/+ (2 mice) and Blimp1^gfp/+ fetal liver stem cells (2 mice), stained as indicated. In the latter 2 mice, GFP⁺ cells were B220⁻ (data not shown). # indicates mouse designation number.