Mll5 mutant mice exhibit reduced blood cell counts and hypocellularity in spleen and thymus. (A) Result of automated blood analysis for hematocrit, erythrocyte, and thrombocyte numbers. (B) Total number of thymocytes and nucleated splenocytes in mice with the indicated genotypes. Only data from litters with at least 1 WT and 1 Mll5^−/− animal are shown. (C) Total number of T cells (CD3⁺), B cells (CD19⁺), and myeloid cells (Gr1⁺Mac1⁺) in spleens of Mll5^−/− mice (▩) and WT littermates (■).