Figure 2
Terminology in MRD measurements. Definitions are based on the presence of blasts on light microscopy examination and disappearance of RT-PCR positivity in a sample with an acceptable sensitivity. RT-PCR panels represent raw data from MRD measurements of a patient using 2 control genes (red and blue curves) and one MRD marker (green curve). Longitudinal measurements represent MRD reporting as recommended by European Leukemia Network4 showing the MRD level (green crosses and lines) as well as the sample day-to-day sensitivity (red diamonds and lines).
