Survival curves of patients with BCL2⁺/MYC⁺ lymphomas according to morphology, bone marrow involvement, MYC translocation partner, and BCL2 protein expression. Median overall survivals are shown in parentheses. (A) Morphology. (B) Bone marrow involvement. (C) MYC translocation partner. (D) BCL2 protein expression (clone 124). In all graphs, x-axis represents cumulative survival; and y-axis, time (years). BCLU indicates B-cell lymphoma unclassifiable; DLBCL, diffuse large B-cell lymphoma; BM^neg, no bone marrow involvement with MYC⁺ lymphoma; BM^pos, bone marrow involvement with MYC⁺ lymphoma; BCL2^neg, no BCL2 protein expression by clone 124; BCL2^pos, BCL2 protein expression by clone 124; and IG/MYC, MYC translocation involving one of the immunoglobulin genes.