Plasma TG and serum CPK levels in subject E. Vertical dotted line represents time of vector administration; TG levels are expressed in millimoles per liter (mM) and CPK in international units per liter (IU/L). *Positive capsid IFN-γ ELISpot. CPK: ULN 190 IU/L; TG: normal levels less than 2 mM, LPL study inclusion criteria more than 10 mM. Mean (± SD) TG prior to gene transfer (week −42 to 0) for subject E was 42.7 mM (± 9.3 mM) (shaded area).