p53 staining of bone marrow biopsies. Immunohistochemistry for p53 on histologic sections of bone marrow biopsies from patients with (A) aplastic anemia, (B) autoimmune hemolytic anemia, (C-D) DBA, and (E-F) MDS with del(5q). (A-F) Original magnification ×400. The samples were analyzed using an Olympus BX41 microscope with the objective lens of 40×/0.75 Olympus UPlanFL (Olympus). The pictures were taken using Olympus QColor5 and analyzed with acquisition software QCapture Pro v6.0 (QImaging) and Adobe Photoshop 6.0.