Tolerance induction by injection of allogeneic APCs. Recipient splenic T cells or mature thymocytes from APC-injected mice were cultured in vitro with splenic APCs derived from B6, BALB/c, or C3H mice for 90 hours. MLR (incorporation of ³H-thymidine) for B6 recipients of B cells (A), GMDCs (B), and BALB/c (C) FLDCs are shown. The data represent the means of triplicate cultures. (D) Percentages of CD4⁺CD25⁺Foxp3⁺ cells in splenocytes of B6 recipients of BALB/c APC subsets (n = 4). Data in all panels are representative of at least 3 independent experiments.