Increased adhesion molecule expression by Rbm15-KO HSCs. (A) Representative flow cytometric analysis of the expression of N-cadherin and β₁ integrin (CD29) on Rbm15-KO and -WT littermate control LSK HSCs (left panels). Bar graphs showing the mean ± SD and P values for results from multiple independent experiments are also included (right panels). (B) N-cadherin expression in RBM15-overexpressing LSK cells. WT Lin⁻ BM cells were transduced with MSCV-IRES-GFP (MIG) vector control or MSCV-IRES-GFP-RBM15 (MIG-RBM15), and then GFP-positive LSKs were gated and the N-cadherin expression was analyzed after 4 days in culture.