Percentage of MBCs, normal BMPCs, and malignant plasma cells (MGUS, MM) as well as HMCLs; ND-WBM and MM-WBM expressing (A) proangiogenic and (B) antiangiogenic genes as judged by PANP. Depicted are only genes found to be expressed at least once in the 113 samples of the training and the 353 samples of the validation group. Proangiogenic genes expressed already at BMPC stage are depicted in gray, aberrantly expressed genes in MMC in light gray, and those significantly overexpressed in MMC with white letters on a dark gray background. Results are listed according to the percentage of BMPC samples, and those aberrantly expressed according to the percentage of MMC samples expressing the respective gene.

*As PANP can only be assessed for U133A and U133 2.0 plus arrays, for probe sets located on the U133B chip presented data are based on the validation group only.