Figure 3
Figure 3. The TMPro variant is a significant determinant of spontaneous metastasis, but not tumor growth. (A) Serial calipation after transplantation of LLCGFP cells into the dorsal subcutis of WT (●, n = 11) and TMPro mice (○, n = 10) revealed no genotype-dependent difference in tumor volume at any time point. Data represent means with SEM. (B) Quantitative analysis of spontaneous pulmonary metastases enumerated 14 days after primary tumor resection.

The TMPro variant is a significant determinant of spontaneous metastasis, but not tumor growth. (A) Serial calipation after transplantation of LLCGFP cells into the dorsal subcutis of WT (●, n = 11) and TMPro mice (○, n = 10) revealed no genotype-dependent difference in tumor volume at any time point. Data represent means with SEM. (B) Quantitative analysis of spontaneous pulmonary metastases enumerated 14 days after primary tumor resection.

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