Clinical effect of new lesions detected by SNP-A karyotyping analysis. Patients with novel lesions detected by SNP-A and normal karyotype (MC) showed worse OS (median, 12 months; OR, 1.81; 95% CI, 1.02-3.35) versus patients without novel SNP lesions (median, 19 months; OR, 0.55; 95% CI, 0.29-0.98; P = .04). Patients with new SNP lesions and those without are represented by gray line (N = 41) and orange line (N = 27), respectively.