Subgroup analysis for OS. A univariate Cox proportional hazards model was used to estimate HRs and the significance of the comparison for OS. The horizontal lines represent 95% CIs for the ratios. All HRs are for patients receiving HD-DN compared with those receiving SD-DN. *Number of patients denotes patients' number for SD-DN/patients' number for HD-DN. ^#OS probability at 5 years. ^$Survival probability at 4 years.