r-hu ADAMTS13 improves performances in the tape removal test after ischemic stroke. Time needed to remove tapes from both the contralateral and ipsilateral paws was recorded on sham-operated mice and mice that underwent MCAO (1 hour) injected intravenously with r-hu ADAMTS13 or vehicle 10 minutes before reperfusion. Global differences between groups were found for each parameter (P < .05).