Viral loads in Foxp3⁺ Treg-depleted and nondepleted DEREG mice. Lymph nodes, spleen, and bone marrow from nondepleted (□) and Foxp3⁺ Treg-depleted (+DT; ■) DEREG mice were assayed for viral loads at 10 dpi. Each column represents a mean number + SEM of infected cells per 1 million nucleated cells for a group of 5 to 7 mice. Data were pooled from 2 independent experiments with similar results. Differences between the groups were analyzed using Student t test. Statistically significant differences between the groups are indicated in the figure.