Analysis of CSR junctions in Art^Δ/− B cells. (A-C) Samples of Sμ-Sγ1, Sμ-Sγ3, and Sμ-Sα CSR junction sequences in Art^Δ/− and Art^fl/− mice. Microhomology is identified by the longest region of homology (1-bp mismatch accepted, underlined nucleotide). Annotated Sμ sequence (top row); CSR junctions (middle row); Sγ1, Sγ3, and Sα sequence (bottom row). Vertical line represents no sequence identity; gray highlight, microhomology; and underlined text, mismatch. Nucleotide overlaps are shown on the right of each sequence. (D) Distribution of microhomology length of Sμ-Sγ1, Sμ-Sγ3, and Sμ-Sαand junctions in Art^Δ/− and Art^fl/− mice. Each triangle represents a unique sequence junction of a given length. Vertical lines and numbers indicate the median microhomology length.