Association of low WBC counts during disease with survival in HIV-infected subjects. Each panel shows Kaplan-Meier (KM) survival plots for subjects with an average WBC count during disease that was < (orange) or ≥ 4000 cells/mm³ (purple). The KM plots are for all subjects (left column), and those with baseline CD4⁺ T-cell counts of < 350 (middle column) ≥ 350 (right column) cells/mm³ in the entire cohort (top row), and subjects categorized as seroconverter (middle row) and seroprevalent (bottom row) component of the cohort. RH indicates relative hazards (reference RH = 1 represents those with WBC counts of ≥ 4000 cells/mm³); CI, confidence interval; P, significance value estimated using Cox proportional hazards modeling; and n, number of subjects.