Longitudinal changes in cardiac R2*. (Left panel) Changes in cardiac R2* mirror changes in pancreatic R2*. Differences have been normalized to the time difference between the observations (ΔR2*/ΔT) and have units of Hertz per year. (Right panel) Changes in cardiac R2* were not predicted by changes in HIC. In particular, negative liver iron balance did not predict a favorable cardiac response, unlike for the pancreas.