Figure 3
![Figure 3. Effect of chelating agents on [Ca2+]i elevations in platelets interacting with acid-soluble type I collagen under flow. Blood cell suspensions (Figure 1 legend contains details) were perfused over collagen at the shear rate of 250 seconds without or with prior treatment with a Ca2+ chelator, the membrane impermeable EGTA (5 mM), the membrane permeable BAPTA-AM (80 μM), or the 2 combined. Results are expressed as described in the legend to Figure 2 (n = 3).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/114/13/10.1182_blood-2008-12-193490/4/zh89990941920003.jpeg?Expires=1744556479&Signature=cmXj1NF2tT4gxXNLH6yI9yO5YiNbUBvfy21Iv8tsSKZqY0B6tLXXe8liP1PpuThxRHZ43uDMQDEuzpnZlIjrI-Cc04TpXx0ROWj0nDS0oW1yqABJ915dfhE0tcGoC9rJDoWPsWeZuD0IvEt5FjLJ7ON3QyqgfFgbyHwPwkJDbx9koW5CUGStAF9Q4gn3FtJi-XdV5yqD1F5kJw4Qx7WIq2VQcu1Qz4dHyBcj81Zh4EVWFjfs1bPPVwQZrxl1C5UKXo8eAfZx8jHzgFnh4BbmcD~I0qSsE9H~ozQrovkeIzlcaTX2N0X3TYt47UADgtOdCNvQIL5-LAh7xcoRPltE2Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of chelating agents on [Ca2+]i elevations in platelets interacting with acid-soluble type I collagen under flow. Blood cell suspensions (Figure 1 legend contains details) were perfused over collagen at the shear rate of 250 seconds without or with prior treatment with a Ca2+ chelator, the membrane impermeable EGTA (5 mM), the membrane permeable BAPTA-AM (80 μM), or the 2 combined. Results are expressed as described in the legend to Figure 2 (n = 3).
