Platelet count and survival. (A) Box plot of platelet count in peripheral blood of WT, WASp KO, WIP KOlow, and WIP KOhigh mice. Circles represent outliers. (B) Platelets were isolated from WT and WASp KO mice, labeled with CMFDA, and injected into 129Sv WT recipients. (C) Platelets were isolated from WT, WIP KOlow, and WIP KOhigh mice, labeled with CMFDA, and injected into 129Sv WT recipients. Results are percentage of positive cells relative to time less than 5 minutes and represent the mean ± SD of 4 transfused mice.