American Society of Hematology

Figure 6

$Figure 6. Alloantigen-specific cytokine-producing cells and relation with number of mismatches on HLA-DR. (A) Flow cytometric example of the IL-2/IFN-γ– and IFN-γ/IL-17–producing cells within the CD154+CD4+ cells for a couple with 0 (Ai and Aii) and 2 (Aiii and Aiv) mismatches (MMs) on HLA-DR, respectively. The results of n = 4 for 0 MM, n = 10 for 1 MM, on HLA-DR and n = 8 for 2 MMs on HLA-DR are displayed. The fraction of (B) IL-2–, (C) IFN-γ–, (D) IL-10–, and (E) IL-17–producing cells within the CD154+CD4+ lymphocytes is shown on the y-axis, whereas on the x-axis the number of MMs on HLA-DR is depicted. Each horizontal line represents the mean. *P < .05.$

Alloantigen-specific cytokine-producing cells and relation with number of mismatches on HLA-DR. (A) Flow cytometric example of the IL-2/IFN-γ– and IFN-γ/IL-17–producing cells within the CD154⁺CD4⁺ cells for a couple with 0 (Ai and Aii) and 2 (Aiii and Aiv) mismatches (MMs) on HLA-DR, respectively. The results of n = 4 for 0 MM, n = 10 for 1 MM, on HLA-DR and n = 8 for 2 MMs on HLA-DR are displayed. The fraction of (B) IL-2–, (C) IFN-γ–, (D) IL-10–, and (E) IL-17–producing cells within the CD154⁺CD4⁺ lymphocytes is shown on the y-axis, whereas on the x-axis the number of MMs on HLA-DR is depicted. Each horizontal line represents the mean. *P < .05.

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