Association between the most noteworthy SNPs in CASP8, CASP9, and CASP1 and risk of NHL by study, NHL subtype, sex, age, and ethnicity, based on the additive model. Square symbols represent odds ratios; symbol size is proportional to number of cases. Horizontal lines represent 95% confidence intervals. The x-axis ranges from an odds ratio of 0.5 to 2.0. Number of cases and controls by study (NCI-SEER: 990 cases, 828 controls; Connecticut: 436 cases, 515 controls; New South Wales: 520 cases, 465 controls); by NHL subtype (DLBCL, n = 600; follicular, n = 540; marginal zone, n = 160; and CLL/SLL, n = 161); by sex (males: 840 cases, 711 controls; females: 1106 cases, 1097 controls); by age (< 50 years: 484 cases, 408 controls; age ≥ 50 years: 1462 cases, 1400 controls); and by ethnicity (non-Hispanic whites: 1751 cases, 1578 controls; all ethnicities combined: 1946 cases, 1808 controls). P values are from additive (ie, trend) model. MAF indicates minor allele frequency.