Relative amount of skipped transcript in CLL specimens. (A) Schematic showing the binding sites of the 2 probes that detect different E-cadherin transcripts. (B) Bar diagram showing selected examples of relative levels of aberrant transcript in normal B cells and CLL specimens relative to their wild-type expression. Numbers above the bars represent aberrant E-cadherin transcript levels. (C) Dot-plot analysis of normal B cells and 26 CLL specimens with E-cadherin expression levels on x-axis and relative aberrant transcript expression on the y-axis. Significant statistical correlation with P = .018.