American Society of Hematology

Figure 5

$Figure 5. Chemokine receptor levels on CLL cells of patients in the study. Surface membrane expression of a panel of chemokine receptors was evaluated in the 13 patients in the study. All the samples were analyzed in the same experiment. (A) Of the chemokine receptor levels studied (see text for the list), only 2 (CCR1 and CXCR1) were expressed at significantly higher densities (MFI) in CD38+ compared with CD38− cells (P < .05). Error bars represent SEs of measurements. (B) Group B patients (n = 4) had significantly higher CXCR4 levels (MFI) compared with group A (n = 9; P = .01). Comparisons of the other chemokine receptors revealed no significant differences between the 2 groups. (C) Both CD38+ (left) and CD38− (right) fractions from group B patients exhibited significantly higher CXCR4 levels compared with the same fractions from group A (P = .02).$

Chemokine receptor levels on CLL cells of patients in the study. Surface membrane expression of a panel of chemokine receptors was evaluated in the 13 patients in the study. All the samples were analyzed in the same experiment. (A) Of the chemokine receptor levels studied (see text for the list), only 2 (CCR1 and CXCR1) were expressed at significantly higher densities (MFI) in CD38⁺ compared with CD38⁻ cells (P < .05). Error bars represent SEs of measurements. (B) Group B patients (n = 4) had significantly higher CXCR4 levels (MFI) compared with group A (n = 9; P = .01). Comparisons of the other chemokine receptors revealed no significant differences between the 2 groups. (C) Both CD38⁺ (left) and CD38⁻ (right) fractions from group B patients exhibited significantly higher CXCR4 levels compared with the same fractions from group A (P = .02).

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