This bone marrow aspirate represents a patient with non-APL AML and shows a marked shift to immaturity that could be easily mistaken for APL. Almost all of the cells are promyelocytes with prominent cytoplasmic granulation. Against the diagnosis of APL is the observation that the nuclei are round to oval in shape and Auer rods are completely absent. In this case, cytogenetic and molecular studies were negative for t(15;17) and the PML/RARα fusion transcript. Wright-Giemsa stain. Slides were viewed with an Olympus BX51 microscope using a 100×/1.4 oil-objective lens. Images were acquired with Olympus DP70 and 71 cameras and Olympus DP70 and 71 software. Images were not manipulated.