Gene expression of the GTPases RhoA, Rac1, and CDC42 and expression of RhoA and Rac1 in MM cell lines and patient samples. (A) Expression of RhoA and Rac1 in MM cell lines (MM1S, OPM2, and RPMI8226) and 3 MM patient samples demonstrating similar expression of both GTPases in all cell lines and patient samples. (B) Gene expression of the GTPases RhoA, Rac1, and CDC42, based on NIH Gene Expression Omnibus database under the accession number GSE6691, demonstrating significant overexpression of RhoA and Rac1, but not CDC42, GTPases in MM samples compared with normal subjects.