Figure 2
Figure 2. The overall, more than VGPR and nCR/CR rates for a selection of phase 2 and phase 3 trials incorporating novel agents. A continuous improvement in response is seen with the combination of newer agents. A cautionary note is that many of these are small single-center experiences, and evidence that early responses translate into longer-term survival is not yet available. References for these trials are as follows: VAD,39 TD,31 RD,40 PAD,37 VTD,6 CVD,38 RVD,36 and CVRD.39

The overall, more than VGPR and nCR/CR rates for a selection of phase 2 and phase 3 trials incorporating novel agents. A continuous improvement in response is seen with the combination of newer agents. A cautionary note is that many of these are small single-center experiences, and evidence that early responses translate into longer-term survival is not yet available. References for these trials are as follows: VAD,39  TD,31  RD,40  PAD,37  VTD, CVD,38  RVD,36  and CVRD.39 

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