The overall, more than VGPR and nCR/CR rates for a selection of phase 2 and phase 3 trials incorporating novel agents. A continuous improvement in response is seen with the combination of newer agents. A cautionary note is that many of these are small single-center experiences, and evidence that early responses translate into longer-term survival is not yet available. References for these trials are as follows: VAD,39 TD,31 RD,40 PAD,37 VTD,6 CVD,38 RVD,36 and CVRD.39