Increase in SDF-1α levels in peripheral blood and bone marrow of patients being differently conditioned. (A) Conditioning regimens in 5 patients undergoing allogeneic stem cell transplantation. Patients gave informed consent according to the institutional guidelines in accordance with the Declaration of Helsinki. (B) Effect of myeloablative and nonmyeloablative regimens on SDF-1 protein levels in peripheral blood and bone marrow. SDF-1 levels (in ng/mL) were determined in both PB plasma and BM plasma before the conditioning regimen (before CR) and at the day of stem cell transplantation (at Tx). *P = .043 BM before conditioning regimen vs PB before conditioning regimen. #P = .043 BM at Tx vs BM before conditioning regimen. ⋀P = .043 BM at Tx vs PB at Tx. ● indicates outlier (before CR; conditioned with myeloablative cyclophosphamide/TBI, at Tx; conditioned with mild nonmyeloablative fludarabine/low-dose TBI). Gray boxes indicate interquartile range (between 75th and 25th percentiles). Horizontal black line through box indicates median. Error bars indicate range.