R-sIL-7gly injection induces chemokine production in organs. CCL19, CCL20, CCL21, and CCL25 mRNAs were quantified in lymph nodes, jejunum, ileum, colon, rectum, lung, and skin from healthy rhesus macaques killed at H0, H24, and D7 after R-sIL-7gly injection. Each symbol represents an individual quantification; gray and white symbols at H24 represent 2 individual macaques. Chemokine mRNA quantifications were normalized to HPRT mRNA in each sample and are presented as fold expression over a reference organ in which the expression of the given chemokine was low and stable over the experiment (ie, jejunum for CCL19, skin for CCL20, and lung for both CCL21 and CCL25). Statistical analyses (Mann-Whitney test) between H0 and either H24 or D7 are shown on top. Horizontal bars represent medians.