Ox-DCs display typical DC functions. (A) Purified T cells were stimulated with graded numbers of allogenic immature DCs or DCs differentiated in the presence of 10, 25, or 40 μg/mL OxPAPC, and the proliferation of T cells was monitored on day 5 of culture by adding [methyl-³H]thymidine followed by measuring [methyl-³H]thymidine incorporation 18 hours later. Data are presented as percent of immature DCs and represent mean values of 3 experiments ± SD. Immature DCs or DCs differentiated in the presence of 10, 25, or 40 μg/mL OxPAPC were incubated with FITC-Dextran (1 mg/mL; B) or mannosylated BSA–FITC (10 μg/mL; C) for 60 minutes and uptake of the fluorescent dyes was measured by flow cytometry. Data are presented as percent of immature DCs and represent mean values of 5 experiments ± SD.