Association of nonpermissive HLA-DPB1 disparities according to TCE4 with increased mortality is seen both in early and in advanced disease. Kaplan-Meier estimates of survival after 10 of 10 or 9 of 10 allele-matched unrelated HSCT for early stage acute leukemia (AL-CR1, n = 81; left panel) or advanced disease (ADV, n = 296; right panel). Transplantations were divided into TCE4-permissive (—) or TCE4-nonpermissive HLA-DPB1 disparities ().