Fluorescence in situ hybridization analysis on interphase and metaphase nuclei (using the LSI IGH/CCND1 XT dual-color, dual-fusion translocation DNA probe) identifying the presence of the t(11;14)(q13;q32) chromosomal translocation. Interphase nuclei are shown in the left panel. One orange (CCND1 on chromosome 11q13), one green (IGH on chromosome 14q32), and 2 fusion signal patterns (der(11) and der(14), indicating the chromosomal rearrangements produced by the translocation) can be observed.