The main gene abnormalities targeting NF-κB pathway are displayed in red and italic font. They result in aberrant activation of noncanonical and canonical NF-κB pathway that together with other signaling pathway activation (JAK/STAT, MAP kinase, PI3K/AKT) trigger myeloma cell survival, proliferation and drug resistance.

The main gene abnormalities targeting NF-κB pathway are displayed in red and italic font. They result in aberrant activation of noncanonical and canonical NF-κB pathway that together with other signaling pathway activation (JAK/STAT, MAP kinase, PI3K/AKT) trigger myeloma cell survival, proliferation and drug resistance.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal