Analysis of the proliferation of erythroblasts (CD71⁺Ter119⁺) in BM and SP from Apc-heterozygous mice. (A) Representative histograms of flow cytometric analysis of the cell cycle in splenic erythroblasts. (B-C) Histograms depicting the cell-cycle status of erythroblasts from (B) BM and (C) SP. Samples were obtained from both Mx1-Cre⁺Apc^fl/+ and Mx1-Cre⁻Apc^fl/+ mice with anemia 4 to 6 months after induction of the Apc deletion (average ± SD of 4-6 animals).*P < .01.