Apc^min bone marrow has enhanced repopulating potential. (A) Whole-blood chimerism (expressed as the fraction of CD45.2-positive donor cells divided by CD45.2 and CD45.1/2 competitor cells) 16 weeks after transplantation into lethally irradiated 45.1 recipients. Representative data of 2 independent experiments. Apc^min 73.1% versus WT 55.9% chimerism, P = .001 (B) Whole-blood chimerism of transplant recipients at 4, 8, and 16 weeks after transplantation. Mean ± SEM (C) Bone marrow chimerism, gated on LKS⁺ cells 16 weeks after transplantation into lethally irradiated recipients. Apc^min 79.8% versus 58.2% WT, P = .015