American Society of Hematology

Figure 1

$Figure 1. Classification of NPM mutant AML samples. The expression of CD34 and CD38 on 8 AML samples is shown. (A) Subtype A samples have CD34 expression less than 0.5% of cells. The phenotypes of 3 subtype A samples are shown (left, sample 1; middle, sample 3; and right, sample 4). (B) Subtype B samples have CD34 expression greater than 0.5%, but the CD34+CD38− population is small (< 0.1%) and distinct from the CD34+CD38+ and CD34− populations. The phenotypes of samples 14 (left) and 15 (right) are shown. (C) Subtype C samples are more heterogeneous than the other subtypes. The CD34+ fraction is greater than 0.5%, but there is no distinct and small CD34+CD38− population. The phenotypes of samples 17 (left), 19 (middle), and 21 (right) are displayed.$

Classification of NPM mutant AML samples. The expression of CD34 and CD38 on 8 AML samples is shown. (A) Subtype A samples have CD34 expression less than 0.5% of cells. The phenotypes of 3 subtype A samples are shown (left, sample 1; middle, sample 3; and right, sample 4). (B) Subtype B samples have CD34 expression greater than 0.5%, but the CD34⁺CD38⁻ population is small (< 0.1%) and distinct from the CD34⁺CD38⁺ and CD34⁻ populations. The phenotypes of samples 14 (left) and 15 (right) are shown. (C) Subtype C samples are more heterogeneous than the other subtypes. The CD34⁺ fraction is greater than 0.5%, but there is no distinct and small CD34⁺CD38⁻ population. The phenotypes of samples 17 (left), 19 (middle), and 21 (right) are displayed.

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