c-mip is up-regulated in the glomeruli of 8 patients with cHL-MCNS. (A) The top panel is representative ISH of c-mip transcript in serial sections from normal human kidney (NHK) and kidney biopsy specimens of patients with I-MCNS and cHL-MCNS. ASP indicates antisense probe; and SP, sense probe. (B) Representative immunohistochemistry on serial sections of normal human kidney and kidney biopsy samples from patients with I-MCNS and cHL-MCNS at an original magnification of ×40. c-mip up-regulation was detected in the podocytes of all patients with cHL-MCNS.