Overall and event-free survival. (A) Kaplan-Meier estimate of overall survival probability of all study patients compared with survival of the normal German male population 2006.³⁴  (B) Event-free survival probability. Event was defined as a severe or fatal infection, severe or fatal bleeding, autoimmunity, malignancy, or death. Each hash mark on a graph line indicates a censored event; # at risk, number of patients at risk at indicated time point.