Tmprss6−/−Hjv−/− and Tmprss6+/+Hjv−/− mice show similar Bmp6 and Id1 levels. (A) Hepatic Bmp6 mRNA expression relative to β-actin mRNA expression in Tmprss6+/+Hjv+/+, Tmprss6−/−Hjv+/+, Tmprss6+/+Hjv−/−, and Tmprss6−/−Hjv−/− mice. (B) Hepatic Id1 mRNA expression relative to β-actin mRNA expression in Tmprss6+/+Hjv+/+, Tmprss6−/−Hjv+/+, Tmprss6+/+Hjv−/−, and Tmprss6−/−Hjv−/− mice. Mean values from analysis of 8-week-old female mice are graphed. For each parameter, 4 female mice per genotype were analyzed. Error bars represent SEM. ‡P < .05 compared with Tmprss6+/+Hjv+/+; *P value not significant compared with Tmprss6+/+Hjv−/−.