Figure 3
Enumeration of absolute numbers of circulating NK-cell subsets in naive and SIV-infected macaques. Absolute numbers of total circulating NK cells were quantified in whole blood as previously described.34 NK subset counts were calculated as fractions of the total absolute counts using frequencies determined by polychromatic flow cytometry (Figure 1). (A) Counts from naive animals are compared with those from chronically infected animals, and only significant P values are shown. Horizontal bars indicate medians. Mann-Whitney test; *P < .05; **P < .01. (B) Absolute counts of peripheral blood DN NK cells correlated with plasma viral loads; Spearman correlation. P < .05 is considered significant.
